Blar i forfatter "Storhaug, Hilde-Merete"

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    • The Association Between Adiponectin, Serum Uric Acid and Urinary Markers of Renal Damage in the General Population: Cross-Sectional Data from the Tromsø Study 

      Solbu, Marit Dahl; Norvik, Jon Viljar; Storhaug, Hilde-Merete; Eriksen, Bjørn Odvar; Melsom, Toralf; Eggen, Anne Elise; Zykova, Svetlana; Kronborg, Jens; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-14)
      Background/Aims: Uric acid may cause renal damage, whereas adiponectin in some studies has been reported to have renoprotective properties. The renoprotective role of adiponectin under the influence of hyperuricemia has not been explored. We assessed the cross-sectional association between adiponectin, serum uric acid (SUA) and urinary biomarkers of glomerular and tubular damage (albumin-creatinine ...

    • Cross-sectional analysis of nutrition and serum uric acid in two Caucasian cohorts: the AusDiab Study and the Tromsø study 

      Zykova, Svetlana; Storhaug, Hilde-Merete; Toft, Ingrid; Chadban, Steven; Jenssen, Trond Geir; White, Sarah L (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-14)
      Background: Hyperuricemia can lead to gout, and may be a risk factor for cardiovascular events, hypertension, diabetes and renal disease. There is well-known link between gout and habitual intake of meat and seafood, however the association between hyperuricemia and micro-and macro-nutrient intake has not been established. <p>Methods: We studied associations between intakes of food categories, ...

    • Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study 

      Norvik, Jon Viljar; Storhaug, Hilde-Merete; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eriksen, Bjørn Odvar; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-10)
      Background: Elevated uric acid (UA) is associated with the presence of the metabolic syndrome (MetS). In a prospective cohort study, we assessed whether baseline and longitudinal change in UA were risk factors for development of MetS and its individual components. <br> Methods: We included 3087 women and 2996 men who had UA measured in the population based Tromsø Study 1994–95. The participants ...

    • Uric acid is a risk factor for ischemic stroke and all-cause mortality in the general population: a gender specific analysis from The Tromsø Study 

      Storhaug, Hilde-Merete; Norvik, Jon Viljar; Toft, Ingrid; Eriksen, Bjørn Odvar; Løchen, Maja-Lisa; Zykova, Svetlana; Solbu, Marit Dahl; White, Sarah; Chadban, S; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: The role of serum uric acid as an independent predictor of cardiovascular disease and death is uncertain in the general population. Adjustments for additional cardiovascular risk factors have not been consistent. We examined the association of serum uric acid with all-cause mortality, ischemic stroke and myocardial infarction in a prospective population based study, with several traditional ...

    • Uric acid is associated with microalbuminuria and decreased glomerular filtration rate in the general population during 7 and 13 years of follow-up: The Tromsø Study 

      Storhaug, Hilde-Merete; Toft, Ingrid; Norvik, Jon Viljar; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf; Løchen, Maja-Lisa; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-11)
      Background: The role of uric acid in development of renal dysfunction (RD) remains controversial. Earlier studies have reported inconsistent results, possibly because of their varying ability to adjust for confounding. The impact of longitudinal change in uric acid on renal outcome has not been assessed previously. We aimed to study the impact of change in serum uric acid (SUA) as well as baseline ...

    • Uric acid predicts mortality and ischaemic stroke in subjects with diastolic dysfunction: the Tromsø Study 1994-2013 

      Norvik, Jon Viljar; Schirmer, Henrik; Ytrehus, Kirsti; Storhaug, Hilde-Merete; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Wilsgaard, Tom; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-31)
      Aims: To investigate whether serum uric acid predicts adverse outcomes in persons with indices of diastolic dysfunction in a general population. <br>Methods and results: We performed a prospective cohort study among 1460 women and 1480 men from 1994 to 2013. End- points were all-cause mortality, incident myocardial infarction, and incident ischaemic stroke. We strati fi ed the analyses ...